Transcranial direct current stimulation can improve the effectiveness of robot-assisted rehabilitation of a hemiplegic upper limb
10.3760/cma.j.issn.0254-1424.2021.09.003
- VernacularTitle:经颅直流电刺激联合上肢机器人训练对脑卒中后偏瘫上肢运动功能影响的磁共振弥散张量成像研究
- Author:
Ting YANG
1
;
Huiyou CHEN
;
Zheng GAO
;
Liang XU
;
Jifa FAN
;
Chenxi XU
;
Xiaoju WANG
Author Information
1. 南京医科大学附属南京医院康复医学科，南京 210006
- Keywords:
Stroke;
Upper limb motor function;
Transcranial direct current stimulation;
Robot-assisted training;
Diffusion tensor imaging
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2021;43(9):781-786
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe any improvement in hemiplegic upper limb functioning when transcranial direct current stimulation (tDCS) is combined with robot-assisted upper limb treatment, and analyze the potential mechanism of neural plasticity through diffusion tensor imaging (DTI).Methods:Twenty stroke survivors with hemiplegia were randomly divided into a treatment group and a control group, each of 10, according to a random number table. Both groups were treated with conventional medication and rehabilitation training using an upper limb robot, while the treatment group also received tDCS daily, with the current increasing from 0 to 1mA over 10 seconds, and then decreasing to 0 over twenty minutes. The experiment lasted for 15 days. The upper extremity portion of the Fugl-Meyer rating scale (UE-FMA) and the Wolf Motor Function Rating Scale (WMFT) were used to evaluate motor functioning before and after the treatment. DTI was also conducted for both groups.Results:After the treatment, the average UE-FMA and WMFT scores of the two groups were significantly higher than before the treatment, with the average UE-FMA score of the treatment group (35.32±13.25), significantly higher than that of the control group (21.80±13.93). After the treatment there were significant differences between the groups in their average FA, rFA and FAasy of the posterior limb of the internal capsule, as well as in FA and the CST length of the central anterior gyrus.Conclusion:tDCS combined with robot-assisted upper limb rehabilitation training can significantly improve the motor functioning of hemiplegic upper limbs, possibly due to neuroplasticity mechanisms that promote CST integrity and symmetry changes. tDCS can be an important adjunct therapy in clinical neurorehabilitation.
