Congenital malignant rhabdoid tumor in a fetal neck: a case report

VernacularTitle:胎儿颈部恶性横纹肌样瘤一例
Author: Bo XIA ¹ ; Qiuming HE ; Junjie WANG ; Junjian LYU ; Jiahua LI
Author Information

1. 广州市妇女儿童医疗中心新生儿外科重症监护室　510623
Keywords: Head and neck neoplasms; Rhabdoid tumor; Fetal diseases
From: Chinese Journal of Perinatal Medicine 2021;24(10):774-777
CountryChina
Language:Chinese
Abstract: We report the clinical characteristics of congenital malignant rhabdoid tumor (MRT) of the neck in a fetus. Prenatal ultrasound and MRI at 33 +4 and 34 weeks gestation revealed a round solid mass on the right side of the fetus' neck. An initial differential diagnosis was between neuroblastoma and vascular malformation. Re-examination with ultrasound at 36 gestational weeks revealed an enlarged fetal neck mass, with concomitant multiple subcutaneous solid masses all over his body, right-side hydrothorax, and abnormal liver echo, which were highly suspicious of metastasis of a malignant tumor. The baby boy was delivered by cesarean section at 37 weeks of gestation with a normal Apgar score and slight shortness of breath. Physical examination showed scattered lesions in the neck, armpits, and limbs, etc. The condition of the infant deteriorated rapidly with the increasing number and volume of the masses after admission. The boy was confirmed as MRT (stage Ⅳ) by pathological biopsy on the left upper arm and died on postnatal day 10 after treatment was withdrawn.