Precision diagnosis of a full-term pregnancy with hydatidiform mole based on postnatal short tandem repeat DNA genotyping: a case report

VernacularTitle:基于DNA短串联重复序列分型分析技术精确诊断足月妊娠合并葡萄胎一例
Author: Liping LIU ¹ ; Nan LU ; Haifeng JIANG ; Minhong PAN ; Lizhou SUN ; Bai JIN
Author Information

1. 南京医科大学第一附属医院　江苏省人民医院产科　210029
Keywords: Pregnancy complications; Hydatidiform mole; Genotyping techniques
From: Chinese Journal of Perinatal Medicine 2021;24(9):685-688
CountryChina
Language:Chinese
Abstract: We describe a case of spontaneous conception following ovarian stimulation, in which a singleton pregnancy was revealed by ultrasound at 17 gestational weeks, with a multi-cystic "honeycomb" pattern in part of the placenta. With close monitoring, the patient delivered a healthy male neonate through cesarean section at 38 gestational weeks. The clinical findings, combined with ultrasound, laboratory, pathological, and immunohistochemistry examination, and short tandem repeat genotyping, confirmed a twin pregnancy consisting of a complete mole and coexisting fetus. No obvious abnormalities were found in the mother or the boy during a four-and-a-half-year's follow-up.