Precision diagnosis of a full-term pregnancy with hydatidiform mole based on postnatal short tandem repeat DNA genotyping: a case report
10.3760/cma.j.cn113903-20201103-01085
- VernacularTitle:基于DNA短串联重复序列分型分析技术精确诊断足月妊娠合并葡萄胎一例
- Author:
Liping LIU
1
;
Nan LU
;
Haifeng JIANG
;
Minhong PAN
;
Lizhou SUN
;
Bai JIN
Author Information
1. 南京医科大学第一附属医院 江苏省人民医院产科 210029
- Keywords:
Pregnancy complications;
Hydatidiform mole;
Genotyping techniques
- From:
Chinese Journal of Perinatal Medicine
2021;24(9):685-688
- CountryChina
- Language:Chinese
-
Abstract:
We describe a case of spontaneous conception following ovarian stimulation, in which a singleton pregnancy was revealed by ultrasound at 17 gestational weeks, with a multi-cystic "honeycomb" pattern in part of the placenta. With close monitoring, the patient delivered a healthy male neonate through cesarean section at 38 gestational weeks. The clinical findings, combined with ultrasound, laboratory, pathological, and immunohistochemistry examination, and short tandem repeat genotyping, confirmed a twin pregnancy consisting of a complete mole and coexisting fetus. No obvious abnormalities were found in the mother or the boy during a four-and-a-half-year's follow-up.