Advances in the prevention of mother-to-child transmission of hepatitis B virus

VernacularTitle:阻断乙型肝炎病毒母婴传播的相关研究进展
Author: Guifang GU ¹ ; Gang QIN ; Chong YU ; Aimin CUI ; Wei YAO ; Yuquan ZHANG
Author Information

1. 南通大学附属医院妇产科　226001
Keywords: Hepatitis B virus; Mother-to-child transmission; Immunization; Antiviral therapy; Prevention strategy
From: Chinese Journal of Perinatal Medicine 2021;24(8):597-600
CountryChina
Language:Chinese
Abstract: Mother-to-child transmission (MTCT) of hepatitis B virus (HBV) represents the most common mode by which children acquire HBV infection. For pregnant women with high viral load and positive hepatitis B e antigen (HBeAg), antiviral therapy during late pregnancy combined with timely and standardized inoculation of neonatal hepatitis B immunoglobulin and hepatitis B vaccine can minimize the possibility of MTCT of HBV. This review focuses on using and withdrawing antiviral drugs during pregnancy, managing postpartum hepatitis, and breastfeeding issues to further optimize the combined immunization and antiviral treatment strategies and seek the optimal solution to preventing MTCT of HBV.