Circadian rhythm disorder of blood pressure in Parkinson′s disease
10.3760/cma.j.cn113694-20210630-00454
- VernacularTitle:帕金森病患者血压昼夜节律紊乱的研究进展
- Author:
Renqing XIAO
1
;
Ying WAN
;
Zhenguo LIU
Author Information
1. 上海交通大学医学院附属新华医院神经内科 200092
- Keywords:
Parkinson disease;
Blood pressure;
Circadian rhythm;
Pathogenesis;
Clinical phenotypes;
Intervention
- From:
Chinese Journal of Neurology
2021;54(12):1307-1311
- CountryChina
- Language:Chinese
-
Abstract:
Circadian rhythm disorder of blood pressure is a common abnormal form of blood pressure in Parkinson′s disease, including abnormal circadian blood pressure pattern, nocturnal hypertension, increased blood pressure variability and awakening hypotension. The pathogenesis of circadian rhythm disorder of blood pressure in Parkinson′s disease is complex, which involves the disruption of circadian rhythm, cardiovascular dysfunction, abnormal hormone secretion and the disorders of sleep-wake cycle and structure. At the same time, it is affected by many factors such as circadian activity rhythm, emotion, anti-Parkinson′s disease drugs and so on. Studies have shown that the circadian rhythm disturbance of blood pressure is closely related to the clinical phenotypes, progression and prognosis of Parkinson′s disease. Therefore, it is suggested to enhance the screening and intervention of circadian rhythm disorders of blood pressure to optimize treatment and improve quality of life in Parkinson′s disease.
