Clinical and electrophysiological study of familial cortical myoclonic tremor with epilepsy with fixation-off sensitivity
10.3760/cma.j.cn113694-20210910-00625
- VernacularTitle:伴失对焦敏感的家族性皮质肌阵挛震颤癫痫的临床和电生理研究
- Author:
Mengmeng HU
1
;
Na YUAN
;
Xiaoli WANG
;
Zezhi WANG
;
Ze CHEN
;
Lei YANG
;
Wanying XU
;
Yonghong LIU
Author Information
1. 空军军医大学西京医院神经内科，西安 710032
- Keywords:
Epilepsies, myoclonic;
Cerebral cortex;
Tremor;
Epilepsy, reflex;
Photophobia;
Fixation-off sensitivity
- From:
Chinese Journal of Neurology
2021;54(12):1249-1255
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discuss the clinical and electrophysiological characteristics of familial cortical myoclonic tremor with epilepsy (FCMTE) with fixation-off sensitivity (FOS).Methods:The clinical and electrophysiological characteristics of four patients diagnosed as FCMTE with FOS in the Electroencephalography (EEG) Monitoring Center of Xijing Hospital from May 2016 to December 2017 were studied and followed up.Results:The four patients were all female. The age was ranged from 29 to 67 years. The course was from six to 30 years, and the follow-up time was at least two years. The tremors and jerks occurred to the four patients frequently when the eyes were closed, which prevented their falling a sleep, and three of them had generalized tonic-clonic seizure occasionally. The FOS was monitored in the all four patients, and the photosensitivity occured to the three of them.Conclusions:The fixation-off sensitive trail during EEG monitoring is helpful to find the FCMTE with FOS. It is necessary to determine the potential clinical significance of FOS and photosensitivity coexisting in patients with FCMTE.
