The utility of quantitative susceptibility mapping in the diagnosis of Wilson′s disease
10.3760/cma.j.cn113694-20201216-00975
- VernacularTitle:定量磁化率成像在肝豆状核变性诊断中的应用
- Author:
Xiangzhen YUAN
1
;
Xiaoping WANG
Author Information
1. 上海交通大学医学院附属同仁医院神经内科 200336
- Keywords:
Hepatolenticular degeneration;
Quantitative susceptibility mapping;
Neuroimaging;
Diagnosis
- From:
Chinese Journal of Neurology
2021;54(9):885-888
- CountryChina
- Language:Chinese
-
Abstract:
Early diagnosis and treatment is the key to improve the prognosis and reduce the disability of Wilson′s disease. Conventional magnetic resonance imaging sequences are difficult to detect early brain lesions in Wilson′s disease, especially in preclinical patients. Quantitative susceptibility mapping (QSM) is a recently developed magnetic resonance post-processing technique, which is very sensitive to magnetic metal deposition in the brain. QSM can be used for quantitative analysis of metal deposition in the basal ganglia of Wilson′s disease and is expected to be an imaging technique for early diagnosis and condition assessment of Wilson′s disease.
