Preliminary evaluation of carotid artery thrombosis by optical coherence tomography
10.3760/cma.j.cn113694-20201112-00870
- VernacularTitle:光学相干断层成像初探颈动脉管腔内血栓特征
- Author:
Xuan SHI
1
;
Yunfei HAN
;
Xiaohui XU
;
Qingwen YANG
;
Rui LIU
;
Fang WANG
;
Chao HOU
;
Qin YIN
;
Ruidong YE
;
Xinfeng LIU
Author Information
1. 南京大学医学院附属金陵医院（东部战区总医院）神经内科 210002
- Keywords:
Thrombosis;
Atherosclerosis;
Carotid arteries;
Optical coherence tomography
- From:
Chinese Journal of Neurology
2021;54(8):808-815
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the morphological features and clinical significance of intra-vascular thrombus in carotid stenosis using optical coherence tomography (OCT).Methods:Twelve patients with carotid artery thrombosis detected by OCT assessment in Jinling Hospital between January 2017 and January 2020 were included. Serial area measurements within the athero-thrombotic target lesion were performed to evaluate the OCT-thrombus score, length, area and volume. The clinical data and plaque morphological features were also assessed.Results:Among the 12 patients demonstrating thrombus on OCT, eight patients presented with white thrombus, two patients presented with red thrombus, and another two patients displayed both white thrombus and red thrombus. OCT-thrombus scores were 1-32. The OCT-thrombus score was correlated to the OCT-thrombus volume ( ρ=0.739, P=0.006) and the thrombus length ( ρ=0.932, P<0.001). All lesions were presented with fibrous cap disruption, and 10 lesions were presented with thin-cap fibroatheroma. In view of the OCT findings, all patients received carotid balloon angioplasty and stent implantation. During an average follow-up of 14.2 months, none of the 12 patients had fatal stroke or recurrent ischemic stroke. Conclusions:OCT can be used to assess intra-carotid thrombus and its more detailed morphological characteristics, offering more possibilities in quantitative analysis of thrombus burden.
