The research progress of the mechanism and treatment for radiation-induced cognitive dysfunction
10.3760/cma.j.cn113694-20201018-00792
- VernacularTitle:放射性认知功能障碍的机制及治疗研究进展
- Author:
Mengmeng WANG
1
;
Yingqi ZHOU
;
Yi HAN
;
Ying CHENG
Author Information
1. 解放军海军特色医学中心高压氧、神经内科，上海200052
- Keywords:
Cognition disorders;
Radiotherapy;
Oxidative stress;
Inflammation
- From:
Chinese Journal of Neurology
2021;54(7):718-722
- CountryChina
- Language:Chinese
-
Abstract:
Radiotherapy is still a major part of the program about treating various head and neck cancers. While improving the survival rate of head and neck cancer patients, radiotherapy can cause the decline of learning, memory, orientation and other functions, seriously, even lead to dementia, namely radiation induced cognitive dysfunction (RICD), which has become a critical factor affecting the quality of life for patients. Because of occult onset and unclear pathogenesis, so far there is few effective preventive and therapeutic tools for RICD. In this paper, the latest research progress on the pathogenesis and treatments of RICD is summarized.
