Report of a case of Leuconostoc lactis bacteremia following intestinal perforation with literature review
10.3760/cma.j.cn114798-20210318-00254
- VernacularTitle:小肠穿孔致明串珠菌血症一例并文献复习
- Author:
Liman HUO
1
;
Zhangying FENG
;
Juan ZHANG
;
Huixian JIA
;
Xiajin ZHOU
;
Bin SHAN
;
Juan HOU
;
Wenli DU
;
Ping LIANG
Author Information
1. 河北医科大学第四医院药学部，石家庄 050011
- Keywords:
Leuconostoc;
Bacteremia;
Intestinal perforation;
Community-acquired infections
- From:
Chinese Journal of General Practitioners
2021;20(11):1176-1179
- CountryChina
- Language:Chinese
-
Abstract:
A 24-year female with abdominal pain and fever for 4 days was admitted. The blood culture showed Leuconostoc growth, and sputum culture showed positive Acinetobacterbaumannii. The diagnosis Leuconostoclactis bacteremia following small intestinal perforation was confirmed; surgical treatment was performed and the infection was controlled by piperacillin sodium and tazobactam combined with tegacycline. Wanfang database, CNKI, PubMed and Embase database up to September 2020 were searched with the keywords of " Leuconostoc lactis" "infection" "bacteraemia" for relevant literature. A total of 32 cases were reported in the literature, of whom 13 (39.4%) were infants, 17 (51.5%) had catheter-related bloodstream infection, and one healthy adult male had bacteremia through gastrointestinal perforation. In 20 patients treated with penicillins-based antibiotics, 18 were cured with an effective rate of 90.0%. The results suggest that Leuconostoc infection is likely to occur in the infants, but adults can still get community-acquired Leuconostoc infection. Most β-lactams are susceptible to Leuconostoc, but some exhibit resistance, so it is recommended to select antimicrobial agents based on drug susceptibility.
