Clinical efficacy of extracorporeal membrane oxygenation on severe acute respiratory distress syndrome caused by Pneumocystis jersima pneumonia after renal transplantation
10.3760/cma.j.cn421203-20201214-00426
- VernacularTitle:ECMO在肾移植术后耶氏肺孢子菌肺炎致重度ARDS中的应用
- Author:
Hongyu WANG
1
;
Sisen ZHANG
;
Xianfa JIAO
;
Qingshan QU
;
Xin JIANG
;
Jiandong ZHANG
Author Information
1. 河南中医药大学人民医院 郑州人民医院重症医学科 450003
- Keywords:
Kidney transplantation;
Extracorporeal membrane oxygen;
Acute respiratory distress syndrome
- From:
Chinese Journal of Organ Transplantation
2021;42(9):524-528
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical efficacy of venovenous extracorporeal membrane oxygenation(V-V ECMO)in patients with severe acute respiratory distress syndrome(ARDS)caused by Pneumocystis pneumonitis(PJP)after kidney transplantation(KT).Methods:Cal data of 9 KT recipients on V-V ECMO were retrospectively analyzed. Timing of V-V ECMO support, complications during treatment and V-V ECMO performance were summarized.Results:All 9 patients with confirmed PJP adopted V-V ECMO with oxygenation index of 25~92 prior to V-V ECMO and average time from admission to initiating V-V ECMO was 5.56(1~17)days. Except for one death from hemorrhagic shock due to abdominal hemorrhage, the remainders were successfully weaned. Another recipient died from sepsis after weaning and there were 7 survivors. V-V ECMO support time was 215.5 h among 8 successfully weaned recipients. Among 7 survivors, 1 had premorbid deterioration of graft function and no fatal complications occurred.Conclusions:V-V ECMO is an effective treatment for severe ARDS caused by P. pneumoniae post-KT. And its early application is recommended for reducing complications and improving patient prognosis.
