Early experience with machine retrograde perfusion of deceased donor kidneys
10.3760/cma.j.cn421203-20201120-00394
- VernacularTitle:器官捐献供者供肾逆行灌注早期经验
- Author:
Jun ZENG
1
;
Zihao JIA
;
Daiwen ZHU
;
Turun SONG
;
Tao LIN
Author Information
1. 四川大学华西医院泌尿外科 泌尿外科研究所 器官移植中心，成都 610041
- Keywords:
Kidney transplantation;
Retrograde flush;
Anterograde flush
- From:
Chinese Journal of Organ Transplantation
2021;42(6):354-358
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the safety and efficacy of retrograde machine perfusion of kidneys from deceased donors.Methods:From January 1, 2020 to July 1, 24 renal transplant recipients underwent organ donation.All grafts were preserved by Kidney Transporter machines(LifePort). Through a random number table, they were divided into two groups of retrograde perfusion(RP group, 12 cases)and anterograde perfusion group(AP group, 12cases). The incidence of delayed recovery of kidney/graft function was compared between two groups.Results:During a follow-up period of 1 month, kidney resistance remained stable in RP group during perfusion.No primary non-function occurred in neither groups.No inter-group difference existed in the incidence of delayed graft function (3 in RP and 2 in AP, P=0.62). At all timepoints within 30 days, both groups had comparable values of urine output, serum creatinine, estimated glomerular filtration rate, cystatin c and blood urea nitrogen.RP group with a resistance index of <0.4 had numerically better kidney function than those with a resistance index of ≥0.4. Conclusions:This novel technique may be an effective and safe alternative for kidney preservation.
