Analysis of middle/long-term clinical efficacy of expanded criteria donor kidney transplantation
10.3760/cma.j.cn421203-20210122-00039
- VernacularTitle:扩大标准的供者肾移植中长期临床疗效分析
- Author:
Bin LIU
1
;
Xin LIAN
;
Shangguo WANG
;
Hang GAO
;
Honglan ZHOU
Author Information
1. 吉林大学第一医院泌尿外科，长春 130021
- Keywords:
Kidney transplantation;
Expanded criteria donor;
Prognosis
- From:
Chinese Journal of Organ Transplantation
2021;42(6):340-343
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the medium/long-term prognosis of kidney transplant recipients with expanded criteria donor(ECD)versus standard criteria donor(SCD).Methods:From August 2011 to May 2017, a total of 506 cases underwent renal transplantation.Based upon baseline clinical data, they were divided into two groups of ECD(67 cases)and SCD(230 cases). And 1: 4 propensity score matching was employed for maximizing the elimination of selection bias influence on the results by rank-sum test.Results:There was no statistical difference existed between ECD and SCD donor kidney in acute rejection, delayed graft function and all-cause infection(all P>0.05). The value of eGFR of ECD donor kidney recipients was slightly lower than that of SCD group at Week 1 and Year 4 postoperatively( P<0.05). And there was no inter-group statistical significance in the fifth year( P=0.273). No significant inter-group difference existed in human/renal survival rate( P=0.143, P=0.076). Conclusions:Appropriate selection criteria and recipient selection criteria can make the application of ECD donor kidney safer and more scientific so as to benefit more patients.
