Application of lung ultrasound score inevaluating patients with primary graft dysfunction after lung transplantation
10.3760/cma.j.cn421203-20200702-00214
- VernacularTitle:肺部B型超声扫描评分在肺移植受者术后原发性移植物功能不全评估中的应用
- Author:
Qiuyue LI
1
;
Siyuan CHANG
;
Gaofeng ZHAO
;
Wei CHANG
;
Gang LIU
;
Gaofei LI
;
Na XU
;
Jingyu CHEN
;
Min FENG
Author Information
1. 郑州大学第一附属医院外科重症监护病房，郑州 450052
- Keywords:
Lung transplantation;
Primary graft dysfunction;
Ultrasonography;
Oxygenation index
- From:
Chinese Journal of Organ Transplantation
2021;42(3):168-172
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application value of bedside lung ultrasound score(LUS)in evaluating patients with primary graft dysfunction(PGD)after lung transplantation.Methods:A total of 35 PGD patients after lung transplantation in surgical intensive care unit from June 2018 to May 2020 were selected as research objects. After lung transplantation, one physician collected the clinical data, including age, gender, preoperative 24 h APACHE II score, postoperative hemodynamic parameters, lactate and respiratory parameters; another physician was responsible for LUS examination and LUS at 12/24/48/72 h post-operation. The correlation between LUS and oxygenation index was analyzed by bivariate correlation analysis. Receiver operating characteristic curve(ROC)was utilized for calculating the predictive value, sensitivity and specificity of LUS score for severe PGD.Results:A negative correlation existed between LUS and oxygenation index in single lung transplant( r=-0.536, P<0.01)and a negative correlation between LUS and oxygenation index ( r=-0.518, P<0.01)in double lung transplant. The area under ROC curve of LUS showed that the predictive value of LUS of severe PGD patients with single lung transplant was 7.0 with a sensitivity of 86.7% and a specificity of 72.1%, the predicted value of LUS of severe PGD in double lung transplant was 13.0 with a sensitivity of 83.3% and a specificity of 60.0%. Conclusions:Lung ultrasound is simple and easy to operate and LUS can evaluate the severity of PGD patients after lung transplantation. It has a high potency of guiding clinical diagnosis and treatment.
