Laparoscopic sleeve gastrectomy in the treatment of obesity with nonalcoholic fatty liver disease
10.3760/cma.j.cn113855-20210809-00478
- VernacularTitle:腹腔镜袖状胃切除术治疗肥胖合并非酒精性脂肪肝的疗效
- Author:
Xinying YU
1
;
Wenmao YAN
;
Lin WANG
;
Youqing XU
;
Rixing BAI
Author Information
1. 首都医科大学附属北京天坛医院消化内科 100070
- Keywords:
Obesity;
Fatty liver;
Gastrectomy
- From:
Chinese Journal of General Surgery
2021;36(11):856-859
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical effect of laparoscopic sleeve gastrectomy (LSG) in the treatment of obesity with non-alcoholic fatty liver disease (NAFLD).Methods:The clinical data of 115 obese patients with NAFLD who underwent LSG surgery at Beijing Tiantan Hospital were analyzed.Results:LSG was successful in a 115 patients, and the body weight and BMI decreased gradually, and were significantly lower than the preoperative level (all P<0.001). EWL% increased and was 73.1%±30.1% at 12 months after operation. The postoperative triglyceride level decreased and was significantly lower than the preoperative level (all P<0.05). Most patients were complicated with abnormal liver function before surgery, and ALT, AST and GGT levels decreased to the normal range 3 months after surgery (all P<0.05). Albumin level was significantly higher 3 months after operation than before operation ( P<0.001). At 12 months postoperatively, the severity grade of fatty liver on ultrasound was significantly lower than that before surgery ( P<0.001). Conclusion:Laparoscopic sleeve gastrectomy can significantly improve lipid metabolism index, liver function index and fatty liver index in NAFLD patients along with weight loss .
