A comparison of clinicopathological features and prognosis between lymph node dissection extents of pancreatic cancer patients undergoing pancreaticoduodenectomy
10.3760/cma.j.cn113855-20210610-00356
- VernacularTitle:胰十二指肠切除术淋巴结清扫与胰头癌临床病理特征及预后的关系
- Author:
Yefan YANG
1
;
Sha ZHAO
;
Yuxi GONG
;
Boya ZHAI
;
Zhihong ZHANG
Author Information
1. 南京医科大学第一附属医院病理学部 210019
- Keywords:
Pancreaticoduodenectomy;
Lymphatic metastasis;
Standard dissection;
Extended dissection
- From:
Chinese Journal of General Surgery
2021;36(11):822-825
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical, pathological features and prognosis of patients who underwent pancreaticoduodenectomy with standard or extended lymph node dissection for pancreatic ductal adenocarcinoma.Methods:A retrospective study was performed on 158 pancreatic head cancer patients who underwent radical resection at the First Affiliated Hospital of Nanjing Medical University from Jul 2017 to Feb 2019. The clinicopathological characteristics and prognosis between the standard dissection group and the extended dissection group were compared. The relationship between the number of examined lymph nodes, positive lymph nodes, and the lymph node ratio, together with their relationship with survival were analyzed.Results:Survival analysis showed no statistical difference in survival between the standard resection group and the extended resection group ( P=0.99). There were statistical differences in gender and age composition between the two group, but no significant differences in operation time, blood loss, or postoperative complications were found. Patients with less examined lymph nodes tended to be of stage N0. examined lymph nodes is positively correlated with positive lymph nodes but is not significantly correlated with lymph node ratio. Positive lymph nodes is strongly correlated with lymph node ratio. The location of lymph node metastasis was not survival-related. Conclusions:There is no prognostic difference between standard lymph node dissection and extended lymph node dissection in pancreatic cancinoma patients after Whipple procedure.
