An analysis of actual 5-year survival after surgical resection of hilar cholangiocarcinoma
10.3760/cma.j.cn113855-20210225-00115
- VernacularTitle:肝门部胆管癌切除术后实际5年生存分析
- Author:
Shuwei LU
1
;
Caide LU
;
Hongchao MI
;
Yong YANG
;
Hongda ZHU
;
Jiongze FANG
Author Information
1. 宁波大学附属李惠利医院肝胆胰外科，浙江省 315040
- Keywords:
Bile duct neoplasms;
Surgical procedures,operative;
5-year survival;
Pathology;
Prognosis
- From:
Chinese Journal of General Surgery
2021;36(11):809-816
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate clinical and pathological factors related to the actual 5-year survival of patients with hilar cholangiocarcinoma (HCC).Methods:A total of 94 HCC patients who underwent radical surgery at the Department of Hepatobiliary and Pancreatic Surgery, Li Huili Hospital of Ningbo Medical Center from Jan 2000 to Jun 2015 were enrolled in this study.Patients were divided into two groups: postoperative survival group beyond 5 years and death group within 5 years. The clinical and pathological features of the two groups were analyzed.Results:Of the 94 patients, 19 (20.2%) had a postoperative survival time of more than 5 years. The actual 5-year overall survival rate of HCC patients (20.2%) was lower than that estimated by Kaplan-Meier survival analysis (22.2%). Gender, age, CEA value, CA199 value, total bilirubin, Child-Pugh classification, Bismuth classification and preoperative jaundice reduction were not significantly different between the two groups nor there were significant difference between two groups in operation time, blood loss, surgical procedure, combined caudate lobectomy, combined pancreaticoduodenectomy, combined resection of surrounding organs, vascular reconstruction and number of bile duct orifices in remnant liver surface. There were significant differences between two groups in the variables of pathological phenotype ( P=0.012), lymph node metastasis ( P=0.001) and resection level ( P=0.048). Conclusion:Non-papillary type, lymph node metastasis and R 1 resection are the independent risk factors of the actual 5-year survival.
