Laparoscopic vs open pancreaticoduodenectomy in the treatment of distal cholangiocarcinoma
10.3760/cma.j.cn113855-20201008-00770
- VernacularTitle:腹腔镜与开腹胰十二指肠切除术治疗远端胆管癌疗效分析
- Author:
Shun CHEN
1
;
Zilong WU
;
Fangming WANG
;
Jun WANG
;
Pin LYU
;
Gang LIANG
;
Bingzhang TIAN
;
Lixue ZHOU
;
Ye OU
;
Feng ZHOU
;
Linhuan LI
Author Information
1. 湖南师范大学附属第一医院（湖南省人民医院）肝胆外科，长沙 410005
- Keywords:
Pancreaticoduodenectomy;
Laparoscopes;
Distal cholangiocarcinoma
- From:
Chinese Journal of General Surgery
2021;36(9):653-657
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare between laparoscopic and open pancreaticoduodenectomy in the treatment of distal cholangiocarcinoma.Methods:The clinical data of laparoscopic pancreaticoduodenectomy (LPD group, n=101) and open pancreaticoduodenectomy (OPD group, n=99) in patients with distal cholangiocarcinoma who underwent pancreaticoduodenectomy at Hunan people's Hospital from Jan 2015 to Dec 2019 were analyzed retrospectively. The operation time, intraoperative blood loss, number of lymph node dissection, R 0 resection rate, postoperative hospital stay, postoperative complications and overall survival rate were compared between the two groups. Results:The operation time was (475.0±90.7) min and (444.8±63.3) min, the intraoperative blood loss was (350.9±397.9) ml and (546.7±642.9) ml, the postoperative hospital stay was (11.5±4.7) d and (13.3±5.1) d, the differences were statistically significant ( P<0.05).The number of lymph node dissection was 14.8±3.0 and 15.4±2.4, the R 0 resection rate was 93.1% and 96.0%, respectively, and there was no significant difference ( P>0.05). There was no significant difference in the incidence of residual complications ( P>0.05). During the follow-up of 5-64 months, the OS of 1, 3 and 5 years in the two groups were 90.4%, 41.3%, 20.6% and 94.3%, 50.8% and 24.7%, respectively. ( P>0.05). Conclusions:LPD is safe and feasible in the treatment of distal cholangiocarcinoma, and its short-term curative effect, curative effect and long-term overall survival rate are similar to those of OPD.
