A comparison between microwave ablation and surgical resection for small hepatocellular carcinoma
10.3760/cma.j.cn113855-20210404-00221
- VernacularTitle:微波消融与手术切除治疗小肝癌的综合疗效比较
- Author:
Qiqi XU
1
;
Weihua ZHU
;
Liyun GAN
;
Dafang ZHANG
;
Shengmin ZHENG
;
Shu LI
;
Xisheng LENG
;
Jirun PENG
Author Information
1. 北京积水潭医院普通外科 100096
- Keywords:
Carcinoma,hepatocellular;
Hepatectomy;
Ablation techniques;
Microwaves
- From:
Chinese Journal of General Surgery
2021;36(9):649-652
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical effects of microwave ablation (MWA) and surgical resection in the treatment of small hepatocellular carcinoma(SHCC).Methods:Sixty five SHCC patients with intact clinical data, treated in the Center of Hepatobiliary Surgery, Peking University People's Hospital between Feb 2005 and Aug 2012, were enrolled in this study. Among them, 30 patients were treated by MWA, and the other 35 by hepatectomy. Follow-up was conducted from Mar 2013 to Feb 2021. The differences in long-term survival, intraoperative blood loss, operative time, postoperative complications, performance status (PS), and postoperative hospital stay were compared between the two groups.Results:The survival probability at 1, 3, 5 and 10 years was 93.2%, 82.5%, 55.6% and 41.2%, respectively, in the MWA group, and 97.1%, 82.6%, 67.2% and 48.3%, in the resection group ( P=0.347). The MWA group had less perioperative complications, less blood loss, shorter operation time, better PS score and better hospital stay than the surgical resection group (all P<0.001).There was no statistically significant difference in the survival rate between BCLC stage 0~A1 and A2~A4 patients( P=0.773, 0.536). Conclusions:Microwave ablation in the treatment of small hepatocellular carcinoma can achieve similar results as hepatectomy with less traumatic,better postoperative PS score and shorter postoperative hospital stay.