Clinicopathological characteristics of papillary thyroid carcinoma in obese children and adolescents
10.3760/cma.j.cn113855-20200916-00714
- VernacularTitle:肥胖儿童和青少年甲状腺乳头状癌患者的临床病理特点分析
- Author:
Weiwei YANG
1
;
Jingtai ZHI
;
Xiangqian ZHENG
;
Wei WANG
Author Information
1. 天津市第一中心医院耳鼻咽喉头颈外科 天津市耳鼻喉科研究所 天津市听觉言语与平衡医学重点实验室 天津市临床重点学科（耳鼻咽喉科学） 天津市耳鼻喉质量控制中心 300192
- Keywords:
Thyroid neoplasms;
Carcinoma, papillary;
Obesity;
Children;
Pathology, clinical
- From:
Chinese Journal of General Surgery
2021;36(6):432-435
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinicopathological characteristics of papillary thyroid carcinoma (PTC) in obese children and adolescents.Methods:From Jan 2012 to Dec 2015, 59 school-age PTC children and adolescents admitted to Tianjin First Central Hospital and Tianjin Medical University Tumor Hospital were recruited for retrospective case-control study. By using the chi-square test, the clinicopathological characteristics of obese children and adolescents with papillary thyroid carcinoma were analyzed. Kaplan-Meier method was used to analyze the factors significantly related to the recurrence.Results:Compared with patients of normal weight, overweight and obese patients were older (χ 2=4.250, P=0.039), and had multifocal tumors (χ 2=5.281, P=0.022) and higher recurernce rate (χ 2=4.861, P=0.027) .Compared with normal-weight children and adolescents with PTC, overweight or obese children and adolescents with PTC significantly had higher recurrence rate (χ 2=4.466, P=0.035); In addition, tumor diameters >1 cm (χ 2=5.453, P=0.020) and patients with multifocal tumors (χ 2=7.218, P=0.007) were also more likely to suffer recurrence. Conclusion:Among children and adolescent patients with papillary thyroid cancer, obesity is significantly related to multifocal tumors and higher recurernce rate.
