A case of cutaneous collagenous vasculopathy
- VernacularTitle:皮肤胶原血管病一例
- Author:
Bingluan LIU
1
;
Xinkai ZHENG
;
Shi WU
;
Jin XU
;
Liehua DENG
;
Yunfeng HU
;
Saijun LIU
Author Information
- Keywords: Telangiectasis; Collagen type IV; Cutaneous collagenous vasculopathy
- From: Chinese Journal of Dermatology 2021;54(7):629-631
- CountryChina
- Language:Chinese
- Abstract: A 22-year-old female patient presented with skin flushing in the bilateral legs for 4 years, which gradually spread throughout the whole lower limbs and forearms 6 months ago. Skin examination showed diffuse flushing and dilated capillaries in the lower limbs and both forearms, and the flushing faded after a press. Histopathological examination of the skin lesion on the leg showed hyperkeratosis in a basket-like shape, increased pigmentation in the basal layer, infiltration of the superficial dermis with scattered lymphocytes, with no obvious red blood cell overflow; periodic acid-Schiff staining showed thickened and homogeneous deposits around the blood vessels; immunohistochemical staining showed thickened blood vessel walls and positive staining for type Ⅳ collagen. Diagnosis: cutaneous collagenous vasculopathy.
