Changes in platelet related parameters in obese patients after sleeve gastrectomy
10.3760/cma.j.cn112138-20210224-00155
- VernacularTitle:肥胖症患者袖状胃切除术后血小板相关指标的改变
- Author:
Yining ZHEN
1
;
Fengying GONG
;
Huijuan ZHU
;
Jianchun YU
;
Weiming KANG
;
Yuxing ZHAO
;
Hongbo YANG
;
Lian DUAN
;
Hui PAN
;
Linjie WANG
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院内分泌科 国家卫生健康委员会内分泌重点实验室 疑难重症及罕见病国家重点实验室100730
- Keywords:
Gastrectomy;
Obesity;
Blood Platelets;
Inflammation
- From:
Chinese Journal of Internal Medicine
2021;60(11):993-996
- CountryChina
- Language:Chinese
-
Abstract:
To compare changes in platelet related parameters in obese patients before and after sleeve gastrectomy (SG), we retrospectively analyzed the clinical data of 31 obese patients who underwent SG in Peking Union Medical College Hospital from December 2012 to September 2020. Results showed that compared with those before surgery, platelet count (PLT) decreased significantly at 2-12 weeks of follow-up ( P=0.009), while platelet distribution width (PDW), mean platelet volume (MPV), and large platelet ratio (P-LCR) increased significantly at the same periods of follow-up after operation ( P<0.001). However, the levels of PDW, MPV, and P-LCR began to decrease at 16-55 weeks when compared with those at 2-12 weeks of follow-up ( P<0.01). PLT was positively correlated with white blood cells and neutrophils at 2-12 weeks of follow-up and positively correlated with high sensitivity C-reactive protein at 16-55 weeks of follow-up after operation ( P<0.05).
