Collateral circulation pathway in patients with basilar artery occlusion/severe stenosis: a single-center case series
10.3760/cma.j.cn112138-20210217-00131
- VernacularTitle:药物或血管内介入治疗基底动脉闭塞/重度狭窄患者的侧支代偿模式
- Author:
Yang BIAN
1
;
Kunyu WANG
;
Yan MIAO
;
Xiaoling ZHONG
;
Shuangshuang JIA
;
Feng QIU
Author Information
1. 解放军总医院第六医学中心神经内科，北京 100048
- Keywords:
Basilar artery;
Vertebrobasilar insufficiency;
Collateral circulation;
Blood flow compensation
- From:
Chinese Journal of Internal Medicine
2021;60(8):734-738
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the collateral circulation compensation model in patients with favorable prognosis of basilar artery occlusion/severe stenosis treated with drugs or endovascular therapy.Methods:Clinical data of patients with basilar artery occlusion/severe stenosis and good clinical outcome were retrospectively collected in the Department of Neurology, Sixth Medical Center of PLA General Hospital from January 2019 to January 2020. They were divided into intensive drug therapy group and combined endovascular therapy group. The number and ways of collateral compensation pathway described by digital substraction angiography (DSA) were analyzed, and the characteristics of the collateral compensation model were summarized. SPSS22.0 software was used for statistical analysis, and the constituent ratio (%) was used for statistical description of the enumeration data.Results:A total of 32 eligible patients were included, including 27 males and 5 females, with an average age 45-76 (59±10) years. The compensation model included posterior communicating artery-posterior cerebral artery (13 cases, 40.6%), posterior communicating artery-posterior cerebral artery-basilar artery (10 cases, 31.2%), cerebellar artery-anastomotic branches of superior cerebellar artery (8 cases, 25.0%), anterior choroid artery-anastomotic branches of posterior choroid artery (2 cases, 6.2%), collateral circulation not established (11 cases, 34.4%).In drug treatment group, collateral compensation was found in the majority (14/15), with mainly posterior communicating artery (10/14).Most patients in combined treatment group did not develop collateral compensation (10/17), anastomotic branches of PICA-SCA were the main routes (6/7).Conclusion:In patients with basilar artery occlusion/severe stenosis, favorable clinical outcome can be achieved in both groups of patients treated with intensive drug therapy or endovascular therapy.
