Advance and prospective of long non-coding RNA in diabetic kidney disease
10.3760/cma.j.cn311282-20201216-00831
- VernacularTitle:长链非编码RNA在糖尿病肾病中的研究进展与展望
- Author:
Mingwei SHAO
1
;
Fangyi WEI
;
Yi SONG
;
Guijun QIN
Author Information
1. 郑州大学第一附属医院内分泌科 450052
- Keywords:
Long non-coding RNA;
Diabetic kidney disease;
Kidney inherent cells;
Macrophages;
Clinical research
- From:
Chinese Journal of Endocrinology and Metabolism
2021;37(11):1020-1024
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the incidence of diabetic kidney disease(DKD) has been increasing gradually, and it has become the leading cause of end-stage renal disease. However, current therapies show limited efficacy in preventing the progression of DKD. Against the backdrop of chip and high-throughput sequencing, long non-coding RNAs are revealed to an important role in the pathogenesis of DKD. This article summarizes the research progress of long non-coding RNA in DKD, and look forward to the more extensive application of long non-coding RNA in the future.
