Impact of the depth of lipohypertrophy assessed by ultrasound on glycemic control in diabetic patients
10.3760/cma.j.cn311282-20201029-00721
- VernacularTitle:超声下胰岛素注射皮下脂肪增生深径对糖尿病患者血糖控制的影响
- Author:
Yun SHI
1
;
Jian YU
;
Hong WANG
;
Min ZHU
;
Dan YAN
;
Min SHEN
;
Yun HUANG
;
Jing HANG
;
Wei HE
;
Jingjing XU
;
Tao YANG
Author Information
1. 南京医科大学第一附属医院内分泌科 210029
- Keywords:
Lipohypertrophy;
Ultrasound;
HbA 1C;
Diabetes mellitus
- From:
Chinese Journal of Endocrinology and Metabolism
2021;37(11):1001-1003
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate the impact of the depth of lipohypertrophy on glycemic control in diabetic patients, 498 diabetic patients were recruited from July 2017 to July 2020 in the First Affiliated Hospital of Nanjing Medical University. Their demographic and clinical data were collected. Lipohypertrophy was assessed with ultrasound. 85.1%(424/498) of patients had lipohypertrophy. The average depth of lipohypertrophy was(5.62±2.49) mm. Compared with HbA 1C≤7%, patients with HbA 1C>7% had significantly higher proportion of lipohypertrophy with depth >5 mm(69.7% vs 81.3%, P<0.05). After adjusting potential confounders, the level of HbA 1C in patients with the depth of lipohypertrophy>5 mm was still significantly higher than those with the depth of lipohypertrophy≤5 mm( OR=1.716, 95% CI 1.104-2.668, P<0.05). The depth of lipohypertrophy may be an independent risk factor for suboptimal HbA 1C. However, prospective studies are still needed to confirm.
