Clinical characteristics and microflora analysis of back abscess in patients with type 2 diabetes mellitus
10.3760/cma.j.cn311282-20200819-00585
- VernacularTitle:2型糖尿病合并背部脓肿临床特点及菌群分析
- Author:
Lifang LYU
1
;
Meng LI
;
Jianjun ZHAO
;
Zhenjun XIE
;
Junfeng WEI
;
Yanan QI
;
Jing LUO
;
Huifeng ZHANG
Author Information
1. 河南省人民医院内分泌科，郑州 450003
- Keywords:
Back abscess;
Diabetes;
Pathogen;
Staphylococcus aureus;
Antibiotics
- From:
Chinese Journal of Endocrinology and Metabolism
2021;37(10):919-923
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively analyze clinical characteristics, flora distribution characteristics, and antimicrobial sensitivity of type 2 diabetic patients with back abscess.Methods:The clinical data of patients with type 2 diabetes mellitus and back abscess were collected from Endocrinology Department of Henan Provincial People′s Hospital from October 2017 to April 2020. The results of bacterial culture and drug sensitivity test were analyzed, antibiotics were given to treat infection, incision and debridement of abscess were performed according to the situation of abscess, drainage of abscess cavity or continuous negative pressure suction was given when necessary, and the clinical outcome was recorded.Results:A total of 12 type 2 diabetic patients with back abscess were included. The average size of their abscess was(150.3±101.2)cm 2, with over 100 cm 2 in 8 cases(66.7%). Among the 12 patients, 11 patients underwent bacterial culture and drug sensitivity analysis. The positive rate of culture was 100%, and all of them were Staphylococcus aureus, with 10 cases of methicillin-susceptible Staphylococcus aureus(MSSA)and 1 case of methicillin-resistant Staphylococcus aureus(MRSA). MSSA strains were 100% sensitive to oxacillin, vancomycin, linezolid, levofloxacin, moxifloxacin, tetracycline, tegecycline, rifampicin, amoxicillin/clavulanic acid, amikacin, and teicoplanin. Both MSSA and MRSA strains were sensitive to vancomycin, linezolid, rifampin, amikacin, and teicoplanin. The wound of all patients was healed, with 100% cure rate and(35.8±34.0)days of average healing time. Conclusion:The back abscess in type 2 diabetic patients is characteristic of rapid progress, huge abscess, and difficult to treat, which should be treated early, incised and debrided timely. Staphylococcus aureus is its single pathogen and it is helpful to select the antibiotics empirically.
