Serum magnesium levels and the prognosis of type 2 diabetes patients with community-acquired pneumonia
10.3760/cma.j.cn311282-20201105-00741
- VernacularTitle:血镁水平对2型糖尿病合并社区获得性肺炎患者预后的影响
- Author:
Siqiong WANG
1
;
Rui WANG
;
Rui WANG
;
Xiaoli LIU
;
Na LU
;
Qiang LU
;
Fuzai YIN
;
Chunming MA
Author Information
1. 秦皇岛市第一医院内分泌科 066000
- Keywords:
Hypomagnesemia;
Diabetes mellitus, type 2;
Community-acquired pneumonia;
Prognosis
- From:
Chinese Journal of Endocrinology and Metabolism
2021;37(9):789-793
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of type 2 diabetes mellitus (T2DM) on the levels of serum magnesium in patients with community-acquired pneumonia (CAP) and the effects of abnormal serum magnesium on the prognosis in T2DM patients with CAP.Methods:The study was a retrospective single-center study conducted in adult patients hospitalized with CAP at the First Hospital of Qinhuangdao between January 2015 and December 2018. These patients were divided into two groups according to the diagnosis of T2DM (control group and T2DM group). The reference range for serum magnesium is from 0.75 to 1.25 mmol/L. The primary endpoint was in-hospital mortality.Results:The prevalences of hypomagnesemia and hypermagnesemia were numerically higher in T2DM group than in control group (hypomagnesemia: 14.6% vs 12.0%, hypermagnesemia: 1.4% vs 0.7%), but there was no statistical difference ( P>0.05). In patients with T2DM, the in-hospital mortalities in patients with normal serum magnesium and hypomagnesemia were 5.9% and 12.7%, respectively; In multivariate logistic regression analysis, the in-hospital mortality of patients with hypomagnesemia was 5.629(95% CI 2.012-15.750, P=0.001)times as much as that of patients with normal serum magnesium. Conclusions:Abnormal serum magnesium was common in T2DM inpatients with CAP and hypomagnesemia was the most common. Hypomagnesemia was closely related to in-hospital mortality in T2DM patients with CAP. The assessment of serum magnesium levels on admission may be helpful in predicting the prognosis of T2DM patients with CAP.
