The progress of renal papillary calcium plaque lesions
10.3760/cma.j.cn112330-20200827-00630
- VernacularTitle:肾乳头钙斑病变的研究进展
- Author:
Qianlin SONG
1
;
Ziqi HE
;
Sixing YANG
Author Information
1. 武汉大学人民医院泌尿外科，武汉 430060
- Keywords:
Renal calculi;
Randall’s plaque;
Renal papillary calcium plaque lesions
- From:
Chinese Journal of Urology
2021;42(10):788-791
- CountryChina
- Language:Chinese
-
Abstract:
The formation mechanism of kidney stones is complex. It is generally recognized that abnormal urine conditions or renal tubular epithelial cell damage, together with other factors cause the formation of renal papillary subepithelial calcium plaques (Randall’s plaques) or stone crystals that block the renal tubules (Randall’s plugs), and then oversaturated crystals gathering on Randall's plaque or plug and forming stones. However, there are many pathophysiological changes and manifestations, such as renal papillary anchoring stones, renal papillary crypts, renal papillary tip erosion, and exogenous renal papilla Renal papillary lesions, which may be an early manifestations before the formation of kidney stones. The study of renal papillary calcium plaque is very important for the pathogenesis of kidney stones, as well as the prevention and treatment of patients with stones. By focusing on the development process of Randall plaque theory, the formation and transformation mechanism of Randall plaque, as well as the manifestations and clinical treatment of the above mentioned different types of renal papillary calcium plaque lesions, this article reviewed three aspects of stone formation, including Randall’s plaque, renal papillary lesions with stones, and renal papillary lesions related to stone.
