The effect of hyperlipidemia on perioperative outcomes of rectal cancer patients
10.3760/cma.j.issn.0254-9026.2021.10.016
- VernacularTitle:高脂血症对直肠癌患者围手术期相关指标的影响
- Author:
Xin WU
1
;
Rongkang KUANG
;
Liyang LIU
;
Haitao YANG
;
Jing TAO
Author Information
1. 南京医科大学第四附属医院普外科，南京 210035
- Keywords:
Hyperlipidemias;
Rectal neoplasms;
Postoperative complications
- From:
Chinese Journal of Geriatrics
2021;40(10):1295-1298
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the influence of hyperlipidemia on perioperative outcomes of rectal cancer patients.Methods:From June 2016 to June 2019, 86 patients who had received laparotomy or laparoscopic radical resection of rectal cancer at the Department of General Surgery of Nanjing Jiangbei People's Hospital were selected as research subjects.Preoperative blood lipids were measured.Based on lipid levels, patients were divided into the hyperlipidemia group(46 cases)and the normal blood lipid group(40 cases). Operative time, intraoperative blood loss, postoperative recovery outcomes, incidence of anastomotic fistula, and incidences of incision fat liquefaction and incision infections were compared between the two groups.SPSS21.0 was used for data analysis.Results:Compared with the normal lipid group, the operative time of the hyperlipidemia group was significantly longer and the amount of intraoperative blood loss was higher in the hyperlipidemia group, and the differences were statistically significant.Compared with the normal lipid group, the hyperlipidemia group showed a longer time to first postoperative flatus and to first postoperative oral intake, delayed drainage tube removal and ambulation, and longer hospital stays, with statistically significant differences.There were 17 cases of postoperative complications in the hyperlipidemia group(37.0%)and 4 cases in the normal lipid group(10.0%), and the difference was statistically significant( χ2=7.027, P=0.008). Conclusions:Hyperlipidemia has adverse effects on surgical outcomes and postoperative recovery for rectal cancer patients.
