Considerations on diagnostic criteria for acute kidney injury in elderly patients and application of novel biomarkers

VernacularTitle:老年急性肾损伤患者的诊断标准选择及新型生物标志物的应用进展
Author: Chen MENG ¹ ; Ban ZHAO ; Yonghui MAO
Author Information

1. 北京医院肾内科　国家老年医学中心　中国医学科学院老年医学研究院　100730
Keywords: Acute kidney injury; Diagnostic criteria; Biological markers
From: Chinese Journal of Geriatrics 2021;40(9):1194-1198
CountryChina
Language:Chinese
Abstract: Acute kidney injury(AKI)refers to a clinical syndrome in which the glomerular filtration rate decreases sharply in a short period of time due to various causes.Since elderly patients often have low renal functional reserve, complex underlying diseases, frequent acute events and various types of drug combinations, the incidence of AKI in elderly patients is significantly higher than that in the general population and trends upward each year.The prevention and treatment of elderly AKI should place an emphasis on the identification of risk factors and early diagnosis.There is considerable controversy over whether the existing real-world diagnostic criteria are clinically practical and appropriate.The application of novel diagnostic biomarkers for the diagnosis of AKI in the elderly population remains to be justified.This paper reviews considerations on the diagnostic criteria for AKI in the elderly and the clinical application of new biomarkers, in order to arrive at improved diagnosis and treatment recommendations.