Frailty syndrome-related biomarkers for the elderly: the latest research progress

VernacularTitle:老年人衰弱综合征组学相关生物学标记物的研究进展
Author: Yiming PAN ¹ ; Yun LI ; Lina MA
Author Information

1. 首都医科大学宣武医院老年医学科，国家老年疾病临床研究中心，北京　100053
Keywords: Frailty; Omics; Biomarkers
From: Chinese Journal of Geriatrics 2021;40(9):1189-1193
CountryChina
Language:Chinese
Abstract: Frailty syndrome is an age-related clinical state of the physiological homeostasis imbalance and the declines in physiological functions.However, the mechanism of frailty is still not clear, and it can only be diagnosed by assessment tools in the clinical research setting without stable and reliable biomarkers.As a new tool, omics platform has made a lot of progress in the field of frailty biomarkers.In this paper, we will review the research status of frailty biomarkers from four aspects including genomics, transcriptomics, proteomics and metabolomics.