Analysis of long-term survival of elderly patients with differentiated thyroid cancer after surgery and its influencing factors
10.3760/cma.j.issn.0254-9026.2021.09.015
- VernacularTitle:老年分化型甲状腺癌患者术后长期生存状况及其影响因素分析
- Author:
Xiaojian ZHANG
1
Author Information
1. 商丘市第一人民医院甲乳外科 476100
- Keywords:
Thyroid neoplasms;
Survival status;
Influencing factors
- From:
Chinese Journal of Geriatrics
2021;40(9):1155-1159
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the long-term survival of elderly patients with differentiated thyroid cancer(DTC)after surgery, and to analyze its influencing factors.Methods:Clinical data of 80 elderly DTC patients from our department who had completed a 5-year post-surgery follow-up between January 2017 and June 2020 were analyzed.The survival characteristics and survival time of patients were analyzed.The difference in mortality was compared in patients with different general conditions.Influencing factors for long-term survival in elderly DTC patients 5 years after surgery were analyzed by using Cox regression.Results:Of 80 elderly DTC patients, the average survival time was 4.53±0.41 years, 18 cases died during the follow-up period, the mortality was 22.50%(18/80), and the survival rate was 77.50%(62/80). Cox regression analysis showed that histological type(follicular thyroid cancer), surgical method(unilateral gland resection), no cervical lymph node dissection and low therapeutic doses of iodine were influencing factors for the long-term survival of elderly DTC patients 5 years after surgery( OR=5.888, 5.795, 6.753 and 4.923, P=0.004, 0.004, 0.002 and 0.003). Conclusions:The 5-year long-term survival of elderly DTC patients may be affected by the histological type, surgical method, cervical lymph node dissection and therapeutic doses of iodine.Clinical management with an emphasis on these factors and with targeted risk mitigation intervention plans may offer a positive impact on the long-term survival for patients.
