Research progress in animal models of sarcopenia
10.3760/cma.j.issn.0254-9026.2021.08.005
- VernacularTitle:肌肉减少症动物模型的研究进展
- Author:
Yan WANG
1
;
Jianxiong MA
;
Benchao DONG
;
Yan LI
;
Hongzhen JIN
;
Guoning QIN
;
Lei SUN
;
Bin LU
;
Aixian TIAN
;
Ying WANG
;
Haohao BAI
;
Xinlong MA
Author Information
1. 天津大学天津医院（天津市天津医院）骨科研究所 天津市骨科生物力学与医学工程重点实验室 300050
- Keywords:
Sarcopenia;
Aging;
Models, animal
- From:
Chinese Journal of Geriatrics
2021;40(8):962-966
- CountryChina
- Language:Chinese
-
Abstract:
Sarcopenia, referred to as myopenia, is a systemic syndrome characterized by decreased muscle mass and muscle strength, and decline of motor function.The elderly are a high incidence group of myopenia.With the aging of the world's population becoming increasingly severe, the incidence rate of sarcopenia has also increased, which has brought a heavy burden to the elderly family and society, and has become an important social health problem for the elderly.At present, there are more and more researches on sarcopenia, but the pathogenic factors of sarcopenia are complex and diverse.The prevention and treatment of sarcopenia still need to be further explored and studied.The establishment of an ideal animal model is the key premise and basis for the related research of sarcopenia.In this paper, the different modeling methods, advantages and disadvantages as well as the scope of application of sarcopenia animal models are described, which can provide reference and help for the subsequent animal experimental research of sarcopenia.
