Research progress on extracellular vesicles in aging and aging-related diseases
10.3760/cma.j.issn.0254-9026.2021.07.025
- VernacularTitle:细胞外囊泡在衰老及衰老相关性疾病中的研究进展
- Author:
Bowen YU
1
;
Jing YANG
;
Chengkui XIU
;
Xue WANG
;
Yan LEI
Author Information
1. 中国中医科学院 医学实验中心北京市中医药防治重大疾病基础研究重点实验室 100700
- Keywords:
Extracellular vesicles;
Aging
- From:
Chinese Journal of Geriatrics
2021;40(7):932-936
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles are spherical membrane vesicles formed by bimolecular lipid layers and are secreted and released into the extracellular environment by many kinds of cells.Extracellular vesicles include exosomes, microparticles and apoptotic bodies, which represent newly discovered ways of intercellular communication and can be used as biomarkers to distinguish a variety of diseases.However, how extracellular vesicles change with age and the underlying mechanisms for these changes are not clear.This article reviews current research on extracellular vesicles, with a focus on the relationship between extracellular vesicles and aging and its role in aging-related diseases.Furthermore, its practical application in aging is also discussed, in order to provide new ideas for the intervention of the aging process and the treatment of aging-related diseases.
