Perioperative safety of pancreaticoduodenectomy in elderly patients
10.3760/cma.j.issn.0254-9026.2021.06.013
- VernacularTitle:老年胰十二指肠切除术患者围术期安全性分析
- Author:
Zhe LI
1
;
Jingyong XU
;
Xiuwen HE
;
Jiangchun QIAO
;
Jinghai SONG
;
Jian CHEN
;
Junmin WEI
Author Information
1. 北京医院普通外科肝胆胰外科 国家老年医学中心 中国医学科学院老年医学研究院
- Keywords:
Pancreaticoduodenectomy;
Intra perioperative
- From:
Chinese Journal of Geriatrics
2021;40(6):752-755
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the perioperative safety of pancreaticoduodenectomy(PD)in elderly patients.Methods:Clinical data of 152 patients undergoing PD in Beijing Hospital between 2016 and 2019 were retrospectively analyzed.According to the age, patients were divided into the elderly group(age≥65 years)and the non-elderly group(age<65 years). The perioperative and postoperative parameters were compared between the two groups.Results:There was no significant difference in the operative time, intraoperative blood loss and intraoperative urine output between the elderly group and the non-elderly group(352.7±69.5)min vs.(359.0±94.4)min, (708.7±672.7) vs.(662.6±896.7)ml and(875.8±497.3)ml vs.(1010.6±568.2)ml, all P>0.05). The perioperative mortality, postoperative complications(Clavien-Dindo classification ≥ grade Ⅲ)and reoperation rate had no significant difference between elderly group and the non-elderly group(6.1% vs.1.2%, 21.2% vs.19.8%, 10.6% vs.8.1%, respectively, χ2=1.487, 0.048 and 0.272, all P>0.05). The incidences of operation-related complications, cardiovascular or cerebrovascular adverse events in elderly group were comparable to non-elderly group( P>0.05). The postoperative hospital stay had no significant difference between the elderly group and the non-elderly group[(28±19)d vs.(27±18)d, P>0.05]. Conclusions:PD is safe in elderly patients.Age is not a contraindication to pancreaticoduodenectomy.The comprehensive systemic evaluation, intraoperative delicate operation and enhanced perioperative management are necessary in the elderly patients undergoing PD.
