Advances on efficacy and mechanism of vitamin D3 in adjuvant therapy of mycobacterium tuberculosis infection
10.3760/cma.j.issn.1674-2397.2021.04.012
- VernacularTitle:维生素D3辅助治疗结核分枝杆菌感染的疗效及作用机制研究进展
- Author:
Yuyuan ZENG
1
;
Jinqiao SUN
Author Information
1. 复旦大学附属儿科医院临床免疫科，上海 201102
- Keywords:
Mycobacterium tuberculosis;
Vitamin D3;
Efficacy;
Innate immune system;
Adaptive immune system
- From:
Chinese Journal of Clinical Infectious Diseases
2021;14(4):314-320
- CountryChina
- Language:Chinese
-
Abstract:
Every year more than 10 million people newly infected with Mycobacterium tuberculosis (MTB) worldwide, which seriously threats human health and life. The anti-MTB infection drugs are constantly developed and updated. Vitamin D3 is a drug which can regulate the immune system, its effect on MTB infection has attracted more and more attention. This article reviews the clinical efficacy of vitamin D3 in adjuvant therapy for MTB infection, and its mechanism in regulating the innate and adaptive immune system, to provide insight for treatment of MTB infection.
