Clinical analysis of 252 patients with tuberculous peritonitis in Wuhu area
10.3760/cma.j.issn.1674-2397.2021.04.006
- VernacularTitle:芜湖地区252例结核性腹膜炎临床分析
- Author:
Jian YANG
1
;
Jianghua YANG
;
Jin DING
;
Lei JIN
;
Huijuan LI
;
Jian SUN
Author Information
1. 皖南医学院第一附属医院感染科，安徽芜湖 241000
- Keywords:
Peritonitis, tuberculous;
Tuberculosis, pulmonary;
Gender;
Age;
Clinical analysis
- From:
Chinese Journal of Clinical Infectious Diseases
2021;14(4):286-292
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical features of tuberculous peritonitis (TBP).Methods:The clinical data of 252 TBP patients admitted to three hospitals in Wuhu area from January 2014 to June 2020 were retrospectively analyzed, and the clinical characteristics of TBP patients of different genders and ages were compared. SPSS 26.0 software was used to analyze the data.Results:Among 252 TBP patients, 130 were males (51.6%) and 122 were females (48.4%). History of abdominal surgery, abdominal masses, reproductive disorders, genital tuberculosis, and delay in diagnosis were more common in female patients (all P<0.01); while fever, cough/sputum expectoration, intestinal tuberculosis and active tuberculosis were more common in male patients (all P<0.01). The proportion of adenosine deaminase in ascites (ADA) ≥35 U/L, strong positive tuberculin test or T-cell spot test in middle-aged and elderly patients was lower than that in young patients ( P<0.01), but there was no significant difference between different genders. Compared with young patients, middle-aged and elderly patients had a low complete response rate, a high proportion of irregular medications, a high incidence of gastrointestinal reactions, liver damage and overall adverse reactions (all P<0.05). Conclusion:Female patients with TBP have fewer symptoms of systemic tuberculosis and high rate of delay in diagnosis, and are prone to complicated with reproductive tuberculosis. In middle-aged and elderly patients with TBP, the sensitivity of ADA and tuberculosis tests is decreased, and the anti-tuberculosis therapy is less effective. The study indicates that the clinical diagnosis and treatment of TBP should be optimized based on the gender and age of patients.
