Association between different paths of diabetic progression and dyslipidemia among adults aged 18 years and above in Nanjing
10.3760/cma.j.cn115624-20210226-00094
- VernacularTitle:南京市居民不同血糖代谢分类与血脂异常的关联性
- Author:
Xin HONG
1
;
Nan ZHOU
;
Jian SU
;
Weiwei WANG
;
Huafeng YANG
;
Shengxiang QI
;
Chenchen WANG
;
Hairong ZHOU
;
Chao LI
;
Qing YE
;
Zhenzhen QIN
;
Jie WU
;
Jinyi ZHOU
Author Information
1. 南京市疾病预防控制中心慢病防制科,南京 210003
- Keywords:
Dyslipidemia;
Diabetes Mellitus;
Cross-sectional studies
- From:
Chinese Journal of Health Management
2021;15(6):551-556
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the association between different paths of diabetic progression and dyslipidemia in a Nanjing adult population.Methods:From January 2017 to June 2018, 61, 098 local residents aged ≥18 years were selected from the Chronic Disease and Risk Factor Surveillance database in Nanjing using a five-stage stratified cluster random sampling method. Data were collected through interview surveys, physical measurements, and laboratory examinations. The relationship between different rates of diabetic progression and dyslipidemia was analyzed using complex weighting and multilevel models.Results:In all, 60, 283 participants were finally enrolled in the study. The weighted proportions of normal glucose regulation, pre-diabetes, and diabetes were 71.2%, 17.9%, and 10.9%, respectively. The overall weighted prevalence, awareness, treatment, and control of dyslipidemia were 29.8%, 41.6%, 28.9%, and 22.9%, respectively. The weighted proportion of patients with dyslipidemia combined with diabetes was 52.9%. The weighted prevalence of dyslipidemia in adults with normal glucose regulation, pre-diabetes, and diabetes was 24.0%, 38.8%, and 52.9%, respectively (all P<0.001). Compared to the normal glucose regulation group, subjects with pre-diabetes ( OR = 2.04, 95% CI: 1.95-2.13) or diabetes ( OR= 3.87, 95% CI: 3.66-4.10) had possibly gradually increased risks of dyslipidemia (all P<0.001). In addition, there was an increasing trend toward awareness, treatment, and control of dyslipidemia with increasing levels of glucose (all P<0.001). The weighted awareness of dyslipidemia in adults with normal glucose regulation, pre-diabetes, and diabetes was 36.3%, 42.8%, and 56.2%, respectively; the corresponding rates of treatment and control were 23.7%, 29.2%, and 43.7%, and 20.4%, 22.6%, and 30.1%, respectively. Conclusion:Diabetes and dyslipidemia have become the main chronic diseases in the Nanjing population.