Application and progress of SPECT in patients with lower extremity artery disease
10.3760/cma.j.cn321828-20200316-00104
- VernacularTitle:SPECT在下肢动脉疾病中的应用及进展
- Author:
Na GUO
1
;
Weifang ZHANG
Author Information
1. 北京大学第三医院核医学科 100191
- Keywords:
Atherosclerosis;
Lower extremity;
Tomography, emission-computed, single-photon;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2021;41(7):431-434
- CountryChina
- Language:Chinese
-
Abstract:
Lower extremity artery disease (LEAD) is a progressive atherosclerotic process that results in progressive limb ischemia leading to life-altering claudication, nonhealing ulcers, limb amputation, which reduces the patient′s quality of life and even threatens life. SPECT can provide noninvasive quantitative evaluation of lower extremity blood perfusion with high sensitivity, and has advantages on patient management, such as early detection, severity evaluation, treatment protocol development and therapeutic effect monitoring. Moreover, radionuclide-labeled molecular targeting imaging agents can directly show ischemia-induced angiogenesis. This article reviews the application and progress of SPECT in LEAD.
