Treatment strategies for acute severe cholangitis
10.3760/cma.j.cn113884-20210128-00035
- VernacularTitle:急性重症胆管炎的处理策略
- Author:
Xinsen XU
1
;
Yingbing LIU
Author Information
1. 上海交通大学医学院附属仁济医院胆胰外科，上海 200127
- Keywords:
Cholangitis;
Cholelithiasis;
Drainage;
Policy
- From:
Chinese Journal of Hepatobiliary Surgery
2021;27(10):789-792
- CountryChina
- Language:Chinese
-
Abstract:
Acute severe cholangitis is a serious disease with fast development and high mortality. The therapeutic options are stills limited. Once diagnosed, the key step of treatment is to timely reduce the high pressure of bile duct caused by biliary obstruction, and to block bacteria and toxins from entering the blood, which might trigger inflammation " cascade reaction" . The policy of " relieve obstruction, remove lesions, and bile duct drainage" raised by academician Huang Zhiqiang, is still the criterion for acute cholangitis treatment. Active biliary drainage, early continuous renal replacement therapy, and simultaneous antibacterial therapy and multi-organ function support can significantly improve the disease outcome and reduce mortality.
