Safety and efficacy of laparoscopic hepatectomy for intrahepatic cholangiocarcinoma
10.3760/cma.j.cn113884-20210118-00025
- VernacularTitle:腹腔镜肝切除术治疗肝内胆管细胞癌的安全性及疗效分析
- Author:
Taian CHEN
1
;
Facai YANG
;
Meng LI
;
Yi HE
;
Li HE
;
Jingdong LI
Author Information
1. 川北医学院附属医院肝胆外一科 川北医学院肝胆胰肠研究所，四川南充 637000
- Keywords:
Cholangiocarcinoma;
Laparoscopy;
Hepatectomy
- From:
Chinese Journal of Hepatobiliary Surgery
2021;27(7):485-488
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the safety and efficacy of laparoscopic liver resection in treatment of intrahepatic cholangiocarcinoma (ICC).Methods:A retrospective study was conducted on the clinicopathological data of 65 patients with ICC who underwent hepatectomy from January 2014 to May 2020 in the Affiliated Hospital of North Sichuan Medical College. There were 37 males and 28 female with an average age of 52 years old. There were 23 patients in the laparoscopy group and 42 patients in the open liver resection (laparotomy) group. The surgical data, complications, long-term recurrence and survival rates were compared between groups.Results:The blood transfusion rate in the laparoscopy group was 8.7% (2/23), which was significantly lower than that in the laparotomy group (16.7% or 7/42) ( P=0.028). The recovery time of gastrointestinal function in the laparoscopy group was (2.8±1.6) days, which was significantly shorter than that in the laparotomy group (4.3±1.1 days, P=0.006). The incidence of complications in the laparotomy group was 31.0% (13/42), which was significantly higher than that in the laparoscopy group (17.4% or 4/23) ( P=0.033). There were 11 patients (47.8%) in the laparoscopy group and 22 patients (52.4%) in the laparotomy group who developed tumor recurrence, with no significant difference in the recurrence rates between the two groups ( P=0.788). The 1, 3, and 5-year cumulative survival rates in the laparoscopy group were 82.6%, 47.8%, and 34.8%, and 83.3%, 42.9%, and 28.6% respectively in the laparotomy group. There were no significant differences in the cumulative survival rates between the two groups ( P=0.494). Conclusions:Laparoscopic radical resection of ICC was technically feasible, safe, and efficacious. Laparoscopic liver resection achieved better results in blood transfusion, gastrointestinal function recovery, and perioperative complications rates than laparotomy.
