Intraoperative surgical factors influencing non-immediate postoperative tracheal extubation after liver transplantation
10.3760/cma.j.cn113884-20210109-00012
- VernacularTitle:影响肝移植受者非术后即刻拔除气管插管的手术相关因素分析
- Author:
Qianqian XU
1
;
Min ZHU
;
Fengyue LIU
;
Yadong WANG
;
Zeyang LIU
;
Chongzhong LIU
Author Information
1. 山东大学齐鲁医院器官移植科,济南 250012
- Keywords:
Liver transplantation;
Airway extubation;
Unhepatic phase;
Intraoperative hypothermia;
Blood loss
- From:
Chinese Journal of Hepatobiliary Surgery
2021;27(7):481-484
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the intraoperative surgical factors which influenced non-immediate postoperative tracheal extubation (IPTE) after liver transplantation.Methods:The clinical data of all liver transplant recipients operated at the Qilu Hospital of Shandong University from January 2011 to July 2019 were reviewed. Patients who returned to a surgical ward with a tracheal cannula or who underwent re-intubation within 48 hours after IPTE because of hypoxemia were assigned to the cannula-preserving group (non-IPTE). The remaining liver recipients were assigned to the control group (IPTE). Univariate and multivariate logistic regression analysis were used to analyze the risk factors influencing IPTE.Results:Of 70 patients enrolled into this study, there were 30 patients in the cannula-preserving group (with 25 males, 5 females, and age of 51.8±7.3). And 40 patients in the control group (with 35 males, 5 females, and age of 48.4±9.6). Univariate logistic regression analysis showed anhepatic phase >45 min, blood loss >800 ml and intraoperative hypothermia were related with non-IPTE after liver transplantation(all P<0.05). Multivariate logistic regression analysis revealed anhepatic phase >45 min ( OR=3.972, 95% CI: 1.193-13.220, P=0.025) and intraoperative hypothermia ( OR=23.682, 95% CI: 2.434-230.438, P=0.006) increased the risk of unsuccessful IPTE. Conclusion:A long anhepatic phase and intraoperative hypothermia were surgical risk factors affecting non-IPTE after liver transplantation. Surgeons should avoid patients having hypothermia and a prolong anhepatic phase during liver transplantation.