Total pancreatectomy in treatment of pancreatic diseases: a single center experience
10.3760/cma.j.cn113884-20201101-00570
- VernacularTitle:全胰切除术治疗胰腺疾病的单中心经验总结
- Author:
Gang LI
1
;
Zhenghua CAI
;
Chenglin LU
;
Yinyin FAN
;
Yudong QIU
;
Shanhua BAO
Author Information
1. 南京大学医学院附属鼓楼医院肝胆胰中心，南京 210008
- Keywords:
Pancreatic diseases;
Pancreatectomy;
Postoperative complications
- From:
Chinese Journal of Hepatobiliary Surgery
2021;27(6):407-410
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To review our clinical experience on total pancreatectomy in treatment of pancreatic diseases.Methods:The clinical data of 25 patients with pancreatic diseases who underwent total pancreatectomy at Nanjing Drum Tower Hospital from February 2016 to October 2019 were retrospectively analyzed. The data on general information, surgical methods, postoperative complications, changes in postoperative pancreatic endocrine and exocrine functions and quality of life were analyzed.Results:There were 16 males and 9 females, aged (60.9±9.4) years. Planned selective surgery was carried out in 16 patients while unplanned operations in 9 patients. There were 15 patients with pancreatic neoplasms with 4 patients who received neoadjuvant or conversion therapy, 6 patients with intraductal papillary mucinous neoplasms, 3 patients with chronic pancreatitis and 1 patient with pancreatic neuroendocrine carcinoma. The total postoperative complication rate was 36% (9/25). One patient died in the perioperative period, and one patient underwent a second operation. After 6 months of operation, 2 of 24 patients had died. The remaining patients had a fasting blood sugar of (8.9±1.6) mmol/L, with an insulin dosage of (30.7±10.6) U/d. The average dosage of trypsin was (1.1±0.3) g/d. The quality of life score reached or exceeded the preoperative levels.Conclusions:Total pancreatectomy was safe and feasible for some pancreatic diseases. For patients with pancreatic cancer, its long-term oncological outcomes need further studies.
