Research progress on biological mechanism of tumor hyperthermia
10.3760/cma.j.cn113030-20210227-00083
- VernacularTitle:肿瘤热疗生物学机制研究进展
- Author:
Pei SHEN
1
;
Xuexiao ZHOU
;
Fan SHI
;
Shengzhi WANG
Author Information
1. 青岛大学口腔医学院 266003
- Keywords:
Neoplasm/hyperthermia;
Immune mechanism;
Apoptosis;
Tumor microenvironment
- From:
Chinese Journal of Radiation Oncology
2021;30(12):1340-1344
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, tumor hyperthermia has become a hot research topic as an adjuvant therapy to traditional tumor therapy. Hyperthermia can directly induce tumor cell necrosis or apoptosis, or inhibit tumor progression by destroying tumor blood vessels. Meantime, it can also activate the response of immune cells and cytokines in the immune system of the host, thereby regulating the immune state of tumor microenvironment. Multiple combined effects influence the tumor progression. A thorough understanding of the biological mechanism of hyperthermia is beneficial to the development of novel therapeutic methods. In this paper, the biological mechanism of hyperthermia in killing tumors was mainly reviewed.
