A Prospective Randomized Open Trial of Nasal Irrigation and Nasal Decongestant for Sinusitis in Children.
- Author:
Yeon Soo CHO
1
;
Min Sung KIM
;
Yoon Hong CHUN
;
Jong seo YOON
;
Hyun Hee KIM
;
Jin Tack KIM
;
Joon Sung LEE
Author Information
1. Department of Pediatrics, School of Medicine, the Catholic University of Korea, Seoul, Republic of Korea. pedjsyoon@catholic.ac.kr
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Sinusitis;
Nasal irrigation;
Nasal decongestant;
Children
- MeSH:
Adenoids;
Amoxicillin;
Anti-Bacterial Agents;
Child;
Humans;
Nasal Lavage;
Prospective Studies;
Sinusitis
- From:Pediatric Allergy and Respiratory Disease
2010;20(4):232-237
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The management of sinusitis in children is controversial. Antibiotic is known as the most essential management. Despite nasal irrigation and nasal decongestant have been used as adjunctive treatments of sinusitis, it is still unclear whether these are effective on sinusitis. Therefore, we used antibiotics with either nasal irrigation and an oral nasal decongestant and tried to estimate the outcome of each case. METHODS: This study was conducted with sinusitis patients who visited our pediatric respiratory disease clinic. They were randomized into 4 groups: Group 1 were treated with a high dose of amoxicillin only; Group 2 were treated with nasal irrigation and a high dose of amoxicillin; Group 3 were treated with a nasal decongestant and a high dose of amoxicillin; and Group 4 were treated with nasal irrigation, a oral nasal decongestant, and a high dose of amoxicillin. Responses to treatment were estimated more than 4 days after the beginning of the therapy in acute or subacute sinusitis, and more than 7 days chronic sinusitis. RESULTS: The responses to the treatments the 4 groups were not comparable. A favorable therapy was not found, regardless of whether a patient had suppurative rhinorrhea, nasal stuffness, typical findings of PNS plain radiograph, or adenoid hypertrophy. CONCLUSION: The use of nasal irrigation or a oral nasal decongestant as an additional therapy to antibiotics for the symptoms of pediatric sinusitis showed no additional effects on sinusitis.
