Clinical application of 3D template-assisted brachytherapy in para-iliac lymph node metastasis
10.3760/cma.j.cn113030-20210204-00061
- VernacularTitle:3D模板辅助插植近距离治疗在髂血管旁转移淋巴结中的临床应用
- Author:
Hongling LU
1
;
Yunchuan SUN
;
Li XIAO
;
Xiaoming YIN
;
Wei GUO
;
Hongjuan YANG
;
Jianxi ZHOU
Author Information
1. 河北省沧州中西医结合医院放疗科 061000
- Keywords:
3D printing template;
Neoplasm metastasis, lymph node/brachytherapy after implantation;
Treatment outcome
- From:
Chinese Journal of Radiation Oncology
2021;30(10):1036-1040
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To preliminarily evaluate the safety and efficacy of 3D printing template-assisted brachytherapy in the treatment of solitary metastatic lymph nodes adjacent to iliac vessels.Methods:Clinical data of 12 cases of para-iliac lymph node metastasis after radiotherapy admitted to our hospital from October 2018 to April 2020 were retrospectively analyzed. All patients received 3D printing template-assisted brachytherapy at a prescription dose of 20-30 Gy/fraction. CT scan was reviewed every 1 month in the first 3 months after treatment and every 3 months at 3 months after treatment.Local control rate, symptom relief rate and adverse events were evaluated.Results:All the 12 patients successfully completed the treatment and follow-up. At 1, 3 and 6 months after 3D printing template-assisted brachytherapy, 2, 2 and 3 patients obtained complete remission of lymph nodes, 9, 8 and 8 cases of partial remission, 1 case of stable disease and no case of disease progression. The symptoms were relieved in 10 patients. Acute radiation enteritis occurred in 2 patients and myelosuppression in 2 patients, which were mitigated after symptomatic treatment.Conclusion:3D printing template-assisted brachytherapy may be an efficacious and safe treatment of para-iliac lymph node metastasis, which yields tolerable adverse events.