Basic research progress on the combination of heavy ion beam and immunotherapy in the treatment of malignant neoplasm
10.3760/cma.j.cn113030-20200929-00487
- VernacularTitle:重离子束联合免疫疗法治疗恶性肿瘤的基础研究进展
- Author:
Yichao GENG
1
;
Qiuning ZHANG
;
Bing LU
;
Xiaohu WANG
Author Information
1. 贵州医科大学附属医院 贵州省肿瘤医院肿瘤科，贵阳 550004
- Keywords:
Malignant neoplasm/heavy ion beam;
Malignant neoplasm/immunotherapy;
Research progress
- From:
Chinese Journal of Radiation Oncology
2021;30(8):867-870
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, heavy ion beams have received great attention in the field of malignant tumor radiotherapy due to their radiation physics and biological characteristics. The high rate of local tumor control is one of its advantages, but the control rate of metastatic lesions is still crucial in the treatment of most malignant tumors. Clinical studies on the combined conventional radiotherapy and immunotherapy suggest that the combination of the two can not only control the primary lesions, but may also reduce or completely eliminate distant metastatic lesions. High linear energy transfer radiation, especially heavy ion beams, may have stronger potential in combined immunotherapy. Therefore, this article focuses on the basic research progress of heavy ion beams regulating anti-tumor immune effects and their combined application with immunotherapy.
