Research progress of chromosome translocation analysis in retrospective biological dose reconstruction
10.3760/cma.j.issn.0254-5098.2021.09.012
- VernacularTitle:染色体易位分析在回顾性生物剂量重建中的研究进展
- Author:
Yumin LYU
1
;
Lin HAN
;
Jie LI
;
Ping WANG
;
Qingjie LIU
Author Information
1. 河南省职业病防治研究院，郑州 450052
- Keywords:
Ionizing radiation;
Chromosome translocation;
Retrospective biodosimetry
- From:
Chinese Journal of Radiological Medicine and Protection
2021;41(9):705-710
- CountryChina
- Language:Chinese
-
Abstract:
The application of chromosome translocation to retrospective biodosimetry for A-bomb survivors, the victims previously exposed to nuclear/ radiation accident has experienced nearly 40 years of development. Retrospective biodosimetry was internationally paid close attention to radiation workers, exposed atomic veterans and medical exposure subjects, respectively, along with the development of molecular cytogenetic technology such as mFISH and cGH. And the remarkable breakthrough and progress have been made in recent years. This paper reviews the progress of translocation indicator as retrospective biodosimetry for the subjects, in order to provide a reference for retrospective dose estimation based on translocation analysis.
