Research progress in the application of exosomes in radiological medicine and underlying mechanisms

VernacularTitle:外泌体在放射医学中的应用与机制研究进展
Author: Yaru YIN ¹ ; Luxun YANG ; Jing LIU ; Binghui LU ; Rong LI
Author Information

1. 陆军军医大学军事预防医学系复合伤研究所　创伤烧伤复合伤国家重点实验室　全军纳米医学重点实验室，重庆　400038
Keywords: Exosomes; Radiation; Bystander effect; Radiation injury; Tumor
From: Chinese Journal of Radiological Medicine and Protection 2021;41(7):547-551
CountryChina
Language:Chinese
Abstract: Nuclear energy is widely used in various fields such as military, medicine, scientific research, industry and agriculture.Nuclear accident may lead to radiation damage to the bodyofpractitioners. At present, the treatment of severe bone marrow radiation sickness is still not ideal.Exosomes are small vesicles with a size of 30-130 nm secreted by living cells and carry a variety of active substances including protein, RNA, DNA, which isimportant medium of intercellular communication.The contents of exosomes can be used not only as biomarkers of radiation damage, but also for the treatment of radiation damage. This article reviewsthe research progress of the application of exosomes in radiological medicine and underlying mechanisms.