High resolution CT findings and clinical features of the novel coronavirus B.1.617.2 variant
10.3760/cma.j.cn112149-20210618-00574
- VernacularTitle:新型冠状病毒B.1.617.2变异株感染者高分辨率CT与临床特点
- Author:
Chengcheng YU
1
;
Yanhong YANG
;
Tianli HU
;
Lieguang ZHANG
;
Songfeng JIANG
;
Bihua CHEN
;
Lin LIN
;
Wanhua GUAN
;
Jinxin LIU
Author Information
1. 广州医科大学附属市八医院放射科510440
- Keywords:
Tomography, X-ray computed;
COVID-19;
B.1.617.2 variant
- From:
Chinese Journal of Radiology
2021;55(10):1054-1058
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate high resolution CT (HRCT) manifestations and clinical features of patients infected with the novel coronavirus B.1.617.2 variant.Methods:A total of 125 patients with the novel coronavirus B.1.617.2 variant in Guangzhou Eighth People′s Hospital from May 21 to June 9, 2021 was enrolled. There were 52 males and 73 females, aged from 1 to 92 years old with a median age of 47 year. The clinical features and HRCT characteristics were analyzed retrospectively.Results:Of the 125 patients, the main clinical manifestations were fever in 54 patients, cough in 50 patients, pharyngeal discomfort in 39 patients, and diarrhea in 5 patients. HRCT showed pneumonia in 96 cases, which predominantly had ground-glass opacities in 92 cases, ground-glass opacities combined with local consolidation in 22 cases, consolidation in 11 cases, intralobular interstitial thickening in 51 cases, centrilobular structural thickening in 23 cases, and cord-like lesions in 33 cases. One patient had pleural effusion, and no enlarged lymph nodes were observed in all patients. The lesions were distributed in the subpleural and/or peripheral lung in 96 cases and along the bronchovascular bundle (middle and inner zone) in 24 cases. The time interval from onset to positive HRCT was 3 (1, 4) days in 96 patients with pneumonia on HRCT. HRCT showed absorption after the imaging findings reaching the peak in 20 patients, and the time interval between the first positive HRCT findings and the peak imaging was 6 (3, 7) days in these 20 patients.Conclusions:The novel coronavirus B.1.617.2 variant has a strong infectivity, short viral latency. Lung injury is decreaseel. People of all ages are susceptible and the diseasemay have rapid pnegression. HRCT mainly shows ground glass opacities, which are more common in subpleural and/or in the lung periphery, with interlobular thickening.